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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DECITABINE
| DECITABINE | ANTINEOPLASTIC | INTRAVENOUS ORAL | Cmax 644 NANOMOLAR VD 299 LITER (65 KILOGRAM) PPB 0 PERCENT Cl 130 LITER / HOUR HT 0.54 HOUR SOLUBILITY SPARINGLY SOLUBLE IN WATER | DEOXYCYTIDINE KINASE | DNA (cytosine-5)-methyltransferase 1 UNIPROT P26358 DNMT1 -- DNA (cytosine-5)-methyltransferase 3A UNIPROT Q9Y6K1 DNMT3A more at DrugCentral | EMA | |||
