DYPHYLLINE DISCONTINUED | DYPHYLLINE | NATURAL MOLECULE (link) ATC R03DA01 ATC R03DB01 ATC R03DA51
RESPIRATORY BRONCHODILATOR AGENTS PHOSPHODIESTERASE INHIBITORS SMOOTH MUSCLE RELAXANTS VASODILATOR AGENTS | ORAL INJECTION | Cmax 67 MICROMOLAR VD 27.3 LITER (65 KILOGRAM) Cl 18.7 LITER / HOUR (65 KILOGRAM) HT 2 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | PHOSPHODIESTERASE PDB 2X0Y (SCREENING-BASED DISCOVERY OF DRUG-LIKE O-GLCNACASE INHIBITOR SCAFFOLDS) LIGAND CODE = X0T (link to the list of PDB complexes) Download experimental 3D coordinates of X0T with added hydrogens | cGMP-inhibited 3,5-cyclic phosphodiesterase A UNIPROT Q14432 PDE3A -- cAMP-specific 3,5-cyclic phosphodiesterase 4B UNIPROT Q07343 PDE4B more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |