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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NEBIVOLOL

NEBIVOLOL


ATC C07AB12
ATC C07FB12
ATC C07BB12
ATC C09DX05
ATC C09BX07

CARDIOVASCULAR
ANTIHYPERTENSIVE
ADRENERGIC BETA-ANTAGONISTS
VASODILATOR AGENTS
BETA BLOCKING AGENTS

ORAL

Tmax 2.75 HOUR

VD 715 LITER (65 KILOGRAM)

PPB 98 PERCENT

Cl 54.6 LITER / HOUR

HT 15.5 HOUR

BETA-1 ADRENERGIC RECEPTOR

Beta-1 adrenergic receptor UNIPROT P08588 ADRB1 -- Beta-2 adrenergic receptor UNIPROT P07550 ADRB2

more at DrugCentral

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ANSM (in French)

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ChEMBL
BindingDB
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