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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CONIVAPTAN

CONIVAPTAN


ATC C03XA02

CARDIOVASCULAR
AQUARESIS PROMOTERS
DIURETICS
VASOPRESSIN RECEPTOR ANTAGONIST

INTRAVENOUS INJECTION

Cmax 1.24 MICROMOLAR

VD 49.4 LITER (65 KILOGRAM)

PPB 99 PERCENT

Cl 15.2 LITER / HOUR

HT 5 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

VASOPRESSIN V1A RECEPTOR
VASOPRESSIN V2 RECEPTOR

VASOPRESSIN V2 RECEPTOR ANTAGONIST CHEMBL1790 VASOPRESSIN V2 RECEPTOR P30518 VASOPRESSIN V2 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE VASOPRESSIN AND OXYTOCIN RECEPTORANSM (in French)

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