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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TINIDAZOLE

TINIDAZOLE


ATC J01XD02
ATC P01AB02
ATC J01RA11
ATC A02BD09
ATC J01RA13

ANTIINFECTIVES
ANTIPROTOZOAL
ALKYLATING AGENTS
ANTITRICHOMONAL AGENTS
FREE NITRO- RADICAL GENERATED AS A RESULT OF THE REDUCTION MAY BE RESPONSIBLE FOR THE ACTIVITY
ANTIMALARIALS
CHEMICALLY REDUCED TINIDAZOLE WAS SHOWN TO RELEASE NITRITES AND CAUSE DAMAGE TO PURIFIED BACTERIAL DNA IN VITRO

ORAL

Cmax 193.1 MICROMOLAR

Tmax 1.6 HOUR

VD 50 LITER

PPB 12 PERCENT

Cl 2.34 LITER / HOUR (65 KILOGRAM)

HT 13.2 HOUR

DNA INHIBITOR CHEMBL2366045 DNA TRICHOMONASANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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