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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TROSPIUM
| TROSPIUM | METABOLISM | ORAL | Cmax 8.9 NANOMOLAR Tmax 5.5 HOUR F 9.6 PERCENT VD 395 LITER PPB 67 PERCENT Cl 13.6 LITER / HOUR (EQN) HT 20 HOUR SOLUBILITY 1 GRAM / 2 MILLILITER | MUSCARINIC ACETYLCHOLINE RECEPTOR M1 | Muscarinic acetylcholine receptor M2 UNIPROT P08172 CHRM2 -- Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3 more at DrugCentral | EMA | |||
