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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DAPTOMYCIN

DAPTOMYCIN


ATC J01XX09

ANTIINFECTIVES
ANTI-BACTERIAL AGENTS
GRAM POSITIVE BACTERIA

INTRAVENOUS

Cmax 113.4 MICROMOLAR (12 MILLIGRAM / KILOGRAM)

VD 6.3 LITER (65 KILOGRAM)

PPB 92 PERCENT

Cl 0.58 LITER / HOUR (65 KILOGRAM)

HT 7.7 HOUR

MEMBRANE

CELL MEMBRANE INHIBITOR CHEMBL2364031 CELL MEMBRANE BACTERIAANSM (in French)

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ChEMBL
BindingDB
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