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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ESZOPICLONE

ESZOPICLONE


ATC N05CF04

NERVOUS SYSTEM
HYPNOTICS AND SEDATIVES
GABA RECEPTOR AGONIST

ORAL

Tmax 1 HOUR

PPB 56 PERCENT

HT 6 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

GABA RECEPTOR

GABA-A RECEPTOR ANION CHANNEL POSITIVE ALLOSTERIC MODULATOR CHEMBL2093872 GABA-A RECEPTOR ANION CHANNEL P14867 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 HOMO SAPIENS ION CHANNEL LGIC GABAAANSM (in French)

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