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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ESZOPICLONE
| ESZOPICLONE | NERVOUS SYSTEM | ORAL | Tmax 1 HOUR PPB 56 PERCENT HT 6 HOUR SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER | GABA RECEPTOR | Gamma-aminobutyric acid receptor subunit alpha-2 UNIPROT P47869 GABRA2 -- Gamma-aminobutyric acid receptor subunit alpha-4 UNIPROT P48169 GABRA4 more at DrugCentral | EMA | |||
