Cheminformatic Tools and Databases for Pharmacology

session 82615 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
EPLERENONE

EPLERENONE


ATC C03DA04

CARDIOVASCULAR
ANTIHYPERTENSIVE
ALDOSTERONE ANTAGONIST

ORAL

Tmax 1.5 HOUR

F 69 PERCENT

VD 66.5 LITER

PPB 50 PERCENT

Cl 10 LITER / HOUR

HT 5 HOUR

SOLUBILITY VERY SLIGHTLY SOLUBLE IN WATER

MINERALOCORTICOID RECEPTOR

PDB 5MWY (THE STRUCTURE OF MR IN COMPLEX WITH EPLERENONE.)

LIGAND CODE = YNU (link to the list of PDB complexes)

Download experimental 3D coordinates of YNU with added hydrogens

MINERALOCORTICOID RECEPTOR ANTAGONIST CHEMBL1994 MINERALOCORTICOID RECEPTOR P08235 MINERALOCORTICOID RECEPTOR HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR3 NR3C NR3C2ANSM (in French)

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SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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