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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ERTAPENEM
| ERTAPENEM | ANTIINFECTIVES | INTRAMUSCULAR INTRAVENOUS | Cmax 174 MICROMOLAR (1 GRAM IV AFTER 2 HOURS) Tmax 2.3 HOUR F 90 PERCENT VD 7.8 LITER (65 KILOGRAM) PPB 90 PERCENT Cl 1.8 LITER / HOUR HT 4 HOUR SOLUBILITY SOLUBLE IN WATER | PENICILLIN-BINDING PROTEIN (PBP) | D-alanyl-D-alanine carboxypeptidase DacB UNIPROT P24228 dacB -- Penicillin-binding protein 1A UNIPROT P02918 mrcA more at DrugCentral | EMA | |||
