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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ABARELIX DISCONTINUED

ABARELIX


ATC L02BX01

ANTINEOPLASTIC
ANTI-TESTOSTERONE AGENTS
GONADOTROPIN-RELEASING HORMONE (GNRH) ANTAGONIST (KD = 0.1 NANOMOLAR)

INTRAMUSCULAR

Cmax 30.6 NANOMOLAR

Tmax 72 HOUR

VD 4040 LITER

Cl 8.6 LITER / HOUR

HT 316 HOUR

GONADOTROPIN-RELEASING HORMONE RECEPTOR

GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONIST CHEMBL1855 GONADOTROPIN-RELEASING HORMONE RECEPTOR P30968 GONADOTROPIN-RELEASING HORMONE RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 PEPTIDE SHORT PEPTIDE GNRH RECEPTORANSM (in French)

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