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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
PIMECROLIMUS

PIMECROLIMUS


ATC D11AX15
ATC D11AH02

DERMATOLOGICALS
IMMUNOSUPPRESSANT
ANTIINFLAMMATORY
TREATMENT OF ATOPIC DERMATITIS

TOPICAL

Cmax 1.72 NANOMOLAR

Tmax 4 HOUR

PPB 99.5 PERCENT

SOLUBILITY INSOLUBLE IN WATER

MACROPHILIN-12 (FKBP-12)

FK506-BINDING PROTEIN 1A INHIBITOR CHEMBL1902 FK506-BINDING PROTEIN 1A P62942 PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FKBP1A HOMO SAPIENS ENZYME ISOMERASEANSM (in French)

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