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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TREPROSTINIL
| TREPROSTINIL | BLOOD | IV SUBCUTANEOUS INHALATION ORAL INTRAVENOUS | Cmax 5.12 NANOMOLAR Tmax 10 HOUR F 100 PERCENT VD 13 LITER (65 KILOGRAM) PPB 91 PERCENT Cl 27.8 LITER / HOUR (65 KILOGRAM) HT 4 HOUR | PROSTACYCLIN RECEPTOR | PROSTANOID IP RECEPTOR AGONIST CHEMBL1995 PROSTANOID IP RECEPTOR P43119 PROSTACYCLIN RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL LIPID-LIKE LIGAND RECEPTOR PROSTANOID RECEPTOR | ANSM (in French) | |||
