Cheminformatic Tools and Databases for Pharmacology

session 18093 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
NATEGLINIDE

NATEGLINIDE


ATC A10BX03

METABOLISM
ANTIDIABETIC
HYPOGLYCEMIC AGENTS
MEGLITINIDES
BINDS ATP-SENSITIVE POTASSIUM (K+ATP) CHANNEL ON PANCREATIC BETA-CELLS

ORAL

Tmax 1 HOUR

F 73 PERCENT

VD 10 LITER

PPB 98 PERCENT

Cl 7 LITER / HOUR

HT 1.5 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL

SULFONYLUREA RECEPTOR 1, Q09428 ATP-BINDING CASSETTE SUB-FAMILY C MEMBER 8 HOMO SAPIENS TRANSPORTER NTPASE ATP BINDING CASSETTE MRPANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |