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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
M TICAGRELOR (is an active metabolite)

TICAGRELOR


ATC B01AC24

BLOOD
P2Y12 PLATELET INHIBITOR
ANTITHROMBOTIC AGENTS

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Cmax 0.55 MICROMOLAR (200 MILLIGRAM) DOI:10.1124/DMD.110.032250

F 36 PERCENT

VD 88 LITER

PPB 99 PERCENT

Cl 6.7 LITER / HOUR (EQN)

HT 9 HOUR

P2Y12 ADP-RECEPTOR

PURINERGIC RECEPTOR P2Y12 NEGATIVE ALLOSTERIC MODULATOR CHEMBL2001 PURINERGIC RECEPTOR P2Y12 Q9H244 P2Y PURINOCEPTOR 12 HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL NUCLEOTIDE-LIKE RECEPTOR PURINE RECEPTORANSM (in French)

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