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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DEXMEDETOMIDINE
| DEXMEDETOMIDINE | NERVOUS SYSTEM | INJECTION INTRAVENOUS BUCCAL SUBLINGUAL | VD 118 LITER PPB 94 PERCENT Cl 39 LITER / HOUR (72 KILOGRAM) HT 2 HOUR SOLUBILITY FREELY SOLUBLE IN WATER | ALPHA-2A ADRENERGIC RECEPTOR | Alpha-2A adrenergic receptor UNIPROT P08913 ADRA2A -- Alpha-2B adrenergic receptor UNIPROT P18089 ADRA2B more at DrugCentral | EMA | |||
