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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| LEVETIRACETAM
| LEVETIRACETAM | NERVOUS SYSTEM | ORAL INTRAVENOUS | Tmax 1 HOUR F 100 PERCENT VD 37.3 LITER (EQN) PPB 10 PERCENT Cl 3.7 LITER / HOUR (65 KILOGRAM) HT 7 HOUR SOLUBILITY VERY SOLUBLE IN WATER (104 GRAM / 100 MILLILITER) | PDB 8JS8 (CRYO-EM STRUCTURE OF SV2A IN COMPLEX WITH BONT, A2 HC AND LEVETIRACETAM) LIGAND CODE = UKX (link to the list of PDB complexes) Download experimental 3D coordinates of UKX with added hydrogens | Synaptic vesicle glycoprotein 2A UNIPROT Q7L0J3 SV2A more at DrugCentral | EMA | |||
