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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CORTISONE (is an active metabolite)
| CORTISONE | METABOLISM | - | GLUCOCORTICOID RECEPTOR PDB 8CC0 (CRYSTAL STRUCTURE OF ANTI-CORTISOL FAB IN COMPLEX WITH CORTISONE) LIGAND CODE = UQC (link to the list of PDB complexes) Download experimental 3D coordinates of UQC with added hydrogens | Glucocorticoid receptor UNIPROT P04150 NR3C1 more at DrugCentral | EMA | ||||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CORTISONE ACETATE DISCONTINUED (has an active metabolite)
| CORTISONE ACETATE | METABOLISM | INJECTION ORAL | SOLUBILITY INSOLUBLE IN WATER | GLUCOCORTICOID RECEPTOR | Glucocorticoid receptor UNIPROT P04150 NR3C1 more at DrugCentral | EMA | |||
