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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ZOLMITRIPTAN

ZOLMITRIPTAN


ATC N02CC03

NERVOUS SYSTEM
ANTIMIGRAINE
ANTI-INFLAMMATORY AGENTS
SELECTIVE SEROTONIN 5-HYDROXYTRYPTAMINE 1B/1D RECEPTOR AGONISTS
VASOCONSTRICTOR AGENTS

ORAL NASAL

Tmax 1.5 HOUR

F 40 PERCENT

VD 455 LITER (65 KILOGRAM)

PPB 25 PERCENT

Cl 122.8 LITER / HOUR

HT 3 HOUR

SOLUBILITY READILY SOLUBLE IN WATER

5-HYDROXYTRYPTAMINE 1B RECEPTOR
5-HYDROXYTRYPTAMINE 1D RECEPTOR

5-hydroxytryptamine receptor 1B UNIPROT P28222 HTR1B -- 5-hydroxytryptamine receptor 1D UNIPROT P28221 HTR1D

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