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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ORLISTAT

ORLISTAT


ATC A08AB01

METABOLISM
ANTIOBESITY
HYPOLIPIDEMIC
COVALENT INHIBITOR OF GASTROINTESTINAL LIPASES
TREATMENT OF OBESITY

ORAL

Tmax 8 HOUR

PPB 99 PERCENT

HT 1.5 HOUR

SOLUBILITY INSOLUBLE IN WATER

GASTRIC LIPASE
PANCREATIC LIPASE

GASTRIC LIPASE INHIBITOR CHEMBL1796 GASTRIC LIPASE P07098 GASTRIC TRIACYLGLYCEROL LIPASE HOMO SAPIENS ENZYME HYDROLASEANSM (in French)

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