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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| CERIVASTATIN DISCONTINUED
| CERIVASTATIN | CARDIOVASCULAR | ORAL | Cmax 27.6 MICROMOLAR Tmax 2 HOUR F 60 PERCENT VD 19.5 LITER (65 KILOGRAM) PPB 99 PERCENT Cl 12.5 LITER / HOUR HT 3 HOUR SOLUBILITY SOLUBLE IN WATER | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE | 3-hydroxy-3-methylglutaryl-coenzyme A reductase UNIPROT P04035 HMGCR more at DrugCentral | EMA | |||
