Cheminformatic Tools and Databases for Pharmacology

session 71313 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
IMIQUIMOD

IMIQUIMOD


ATC D06BB10

DERMATOLOGICALS
IMMUNOMODULATOR
ANTIVIRAL
ADJUVANTS, IMMUNOLOGIC
ANTINEOPLASTIC AGENTS
INTERFERON INDUCERS
TREATMENT OF ACTINIC KERATOSIS, UPERFICIAL BASAL CELL CARCINOMA AND EXTERNAL GENITAL WARTS
TOLL-LIKE RECEPTOR 7 AGONIST THAT ACTIVATES IMMUNE CELLS

TOPICAL

Cmax 1.34 NANOMOLAR

Tmax 9 HOUR

HT 29.3 HOUR

TOLL-LIKE RECEPTOR 7

PDB 5LBT (STRUCTURE OF THE HUMAN QUINONE REDUCTASE 2 (NQO2) IN COMPLEX WITH IMIQUIMOD)

LIGAND CODE = 6T0 (link to the list of PDB complexes)

Download experimental 3D coordinates of 6T0 with added hydrogens

Toll-like receptor 7 UNIPROT Q9NYK1 TLR7

more at DrugCentral

EMA

ANSM (in French)

Inxight Drugs
Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |