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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TROGLITAZONE DISCONTINUED

TROGLITAZONE


ATC A10BG01

METABOLISM
ANTIDIABETIC
HYPOGLYCEMIC AGENTS
PPAR AGONIST

ORAL

Cmax 6.39 MICROMOLAR (600 MILLIGRAM)

VD 1202 LITER (65 KILOGRAM)

PPB 99 PERCENT

Cl 29.7 LITER / HOUR

HT 25 HOUR

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (PPAR)

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA AGONIST CHEMBL235 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA P37231 PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR1 NR1C NR1C3ANSM (in French)

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