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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
MODAFINIL

MODAFINIL
ARMODAFINIL


ATC N06BA07

NERVOUS SYSTEM
CNS STIMULANT
TARGETS UNKNOWN
ANOREXIGENIC AGENTS
MODAFINIL HAS WAKE-PROMOTING ACTIONS SIMILAR TO SYMPATHOMIMETIC AGENTS LIKE AMPHETAMINE
RACEMIC L-ISOMER AND D-ISOMER DO NOT INTERCONVERT

ORAL

Tmax 3 HOUR

VD 58 LITER (65 KILOGRAM)

PPB 60 PERCENT

Cl 2.6 LITER / HOUR (EQN)

HT 15 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

DOPAMINE TRANSPORTER INHIBITOR CHEMBL238 DOPAMINE TRANSPORTER Q01959 SODIUM-DEPENDENT DOPAMINE TRANSPORTER HOMO SAPIENS TRANSPORTER ELECTROCHEMICAL SLC SLC06ANSM (in French)

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