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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
GREPAFLOXACIN DISCONTINUED

GREPAFLOXACIN


ATC J01MA11

ANTIBIOTIC
ANTIBACTERIAL
ANTIINFECTIVES
INHIBITOR

ORAL

Cmax 4.9 MICROMOLAR (400 MG - 600 MG)

F 70 PERCENT

VD 325 LITER (65 KILOGRAM)

PPB 50 PERCENT

Cl 15 LITER / HOUR (EQN)

HT 15 HOUR

SOLUBILITY SOLUBLE IN WATER

DNA TOPOISOMERASE II (DNA GYRASE)
DNA TOPOISOMERASE IV

DNA GYRASE INHIBITOR CHEMBL2311225 DNA GYRASE P0A4L9 DNA GYRASE SUBUNIT B STREPTOCOCCUS PNEUMONIAE ENZYME ISOMERASEANSM (in French)

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