| | ||||||||||
| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| MIGLITOL
| MIGLITOL | METABOLISM | ORAL | Tmax 2.5 HOUR VD 11.7 LITER (65 KILOGRAM) PPB 4 PERCENT Cl 6.6 LITER / HOUR (65 KILOGRAM) HT 2 HOUR SOLUBILITY SOLUBLE IN WATER | ALPHA-GLUCOSIDASE PDB 5NN6 (CRYSTAL STRUCTURE OF HUMAN LYSOSOMAL ACID-ALPHA-GLUCOSIDASE, GAA, IN COMPLEX WITH N-HYDROXYETHYL-1-DEOXYNOJIRIMYCIN) LIGAND CODE = MIG (link to the list of PDB complexes) Download experimental 3D coordinates of MIG with added hydrogens | Maltase-glucoamylase, intestinal UNIPROT O43451 MGAM -- Lysosomal alpha-glucosidase UNIPROT P10253 GAA more at DrugCentral | EMA | |||
