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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| SPARFLOXACIN DISCONTINUED
| SPARFLOXACIN | ANTIINFECTIVES | ORAL | Cmax 3.3 MICROMOLAR Tmax 4.5 HOUR F 92 PERCENT VD 253 LITER (65 KILOGRAM) PPB 45 PERCENT Cl 11.4 LITER / HOUR HT 20 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | DNA GYRASE | Topoisomerase IV UNIPROT P0AFI2 parC -- DNA gyrase UNIPROT P0AES4 gyrA more at DrugCentral | EMA | |||
