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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
SPARFLOXACIN DISCONTINUED

SPARFLOXACIN


ATC J01MA09

ANTIINFECTIVES
ANTIBIOTIC
ANTIBACTERIAL AGENTS
DNA GYRASE (A BACTERIAL TOPOISOMERASE) INHIBITOR

ORAL

Cmax 3.3 MICROMOLAR

Tmax 4.5 HOUR

F 92 PERCENT

VD 253 LITER (65 KILOGRAM)

PPB 45 PERCENT

Cl 11.4 LITER / HOUR

HT 20 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

DNA GYRASE

BACTERIAL DNA GYRASE INHIBITOR CHEMBL2311224 BACTERIAL DNA GYRASE P0AES4 DNA GYRASE SUBUNIT A BACTERIA ENZYME ISOMERASEANSM (in French)

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