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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ROPINIROLE

ROPINIROLE


ATC N04BC04

NERVOUS SYSTEM
ANTIDYSKINETICS
ANTIPARKINSON AGENTS
NON-ERGOLINE DOPAMINE AGONISTS

ORAL

Tmax 1.5 HOUR

F 55 PERCENT

VD 487.5 LITER (65 KILOGRAM)

PPB 40 PERCENT

Cl 47 LITER / HOUR

HT 6 HOUR

SOLUBILITY OF 133 MILLIGRAM / MILLILITER IN WATER

D(3) DOPAMINE RECEPTOR
D(2) DOPAMINE RECEPTOR

D(2) dopamine receptor UNIPROT P14416 DRD2

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