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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| PENCICLOVIR (is an active metabolite) (has an active metabolite)
| PENCICLOVIR | ANTIINFECTIVES | TOPICAL | Cmax 15.8 MICROMOLAR Tmax 0.7 HOUR VD 71.5 LITER (65 KILOGRAM) PPB 14 PERCENT Cl 32.7 LITER / HOUR (65 KILOGRAM) HT 2.1 HOUR SOLUBILITY OF 1.7 MILLIGRAM / MILLILITER IN WATER | THYMIDINE KINASE | DNA polymerase catalytic subunit UNIPROT P04293 more at DrugCentral | EMA | |||
