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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ANASTROZOLE

ANASTROZOLE


ATC L02BG03

ANTINEOPLASTIC
AROMATASE INHIBITORS
HORMONE RECEPTOR-POSITIVE EARLY BREAST CANCER

ORAL

Tmax 2 HOUR

PPB 40 PERCENT

HT 50 HOUR

SOLUBILITY 0.5 MILLIGRAM / MILLILITER IN WATER

CYTOCHROME P450 19 (AROMATASE)

CYTOCHROME P450 19A1 INHIBITOR CHEMBL1978 CYTOCHROME P450 19A1 P11511 AROMATASE HOMO SAPIENS ENZYME CYTOCHROME P450 CYP_19 CYP_19A CYP_19A1ANSM (in French)

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