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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
FEXOFENADINE

FEXOFENADINE


ATC R06AX26

RESPIRATORY SYSTEM
NON-SEDATING H1 HISTAMINE ANTAGONIST
ANTI-ALLERGIC AGENTS

ORAL

Cmax 820 NANOMOLAR

Tmax 2.6 HOUR

PPB 65 PERCENT

HT 14.4 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

HISTAMINE H1 RECEPTOR

HISTAMINE H1 RECEPTOR ANTAGONIST CHEMBL231 HISTAMINE H1 RECEPTOR P35367 HISTAMINE H1 RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR HISTAMINE RECEPTORANSM (in French)

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