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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| TRANDOLAPRIL (has an active metabolite)
| TRANDOLAPRIL | CARDIOVASCULAR | ORAL | Tmax 1 HOUR F 10 PERCENT VD 18 LITER PPB 80 PERCENT Cl 52 LITER / HOUR HT 6 HOUR | ANGIOTENSIN-CONVERTING ENZYME | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR CHEMBL1808 ANGIOTENSIN-CONVERTING ENZYME P12821 ANGIOTENSIN-CONVERTING ENZYME HOMO SAPIENS ENZYME PROTEASE METALLO MAE M2 | ANSM (in French) | |||
