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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BUTENAFINE

BUTENAFINE


ATC D01AE23

DERMATOLOGICALS
ANTIFUNGAL
INHIBITING THE EPOXIDATION OF SQUALENE THUS BLOCKING THE BIOSYNTHESIS OF ERGOSTEROL

TOPICAL

Cmax 4.4 NANOMOLAR

Tmax 15 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

SQUALENE EPOXIDASE

SQUALENE MONOOXYGENASE INHIBITOR CHEMBL2364679 SQUALENE MONOOXYGENASE Q4JEY0 SQUALENE EPOXIDASE TRICHOPHYTON ENZYME REDUCTASEANSM (in French)

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