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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ZILEUTON
| ZILEUTON | ANTIINFLAMMATORY | ORAL | Cmax 21.1 MICROMOLAR Tmax 1.7 HOUR VD 78 LITER (65 KILOGRAM) PPB 93 PERCENT Cl 27.3 LITER / HOUR (65 KILOGRAM) HT 2.5 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | 5-LIPOXYGENASE | Arachidonate 5-lipoxygenase UNIPROT P09917 ALOX5 more at DrugCentral | EMA | |||
