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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DOCETAXEL
| DOCETAXEL | ANTINEOPLASTIC | INJECTION INTRAVENOUS | VD 113 LITER PPB 97 PERCENT Cl 33.8 LITER / HOUR HT 11 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | TUBULIN PDB 1TUB (TUBULIN ALPHA-BETA DIMER, ELECTRON DIFFRACTION) LIGAND CODE = TXL (link to the list of PDB complexes) Download experimental 3D coordinates of TXL with added hydrogens | Tubulin beta UNIPROT P07437 TUBB more at DrugCentral | EMA | |||
