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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
STAVUDINE

STAVUDINE


ATC J05AF04
ATC J05AR07

ANTIINFECTIVES
ANTIVIRAL
ANTI-HIV AGENTS
ANTIMETABOLITES
NUCLEOSIDE AND NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS

ORAL

Cmax 2.4 MICROMOLAR

Tmax 1 HOUR

F 86 PERCENT

VD 46 LITER

PPB 0 PERCENT

Cl 35.6 LITER / HOUR

HT 1.6 HOUR

SOLUBILITY 83 MILLIGRAM / MILLILITER IN WATER

HIV REVERSE TRANSCRIPTASE (GAG-POL POLYPROTEIN)

HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE INHIBITOR CHEMBL247 HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE Q72547 REVERSE TRANSCRIPTASE/RNASEH HUMAN IMMUNODEFICIENCY VIRUS 1 ENZYME HYDROLASEANSM (in French)

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