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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DORZOLAMIDE
| DORZOLAMIDE | SENSORY | OPHTHALMIC | PPB 33 PERCENT HT 2880 HOUR SOLUBILITY SOLUBLE IN WATER | CARBONIC ANHYDRASE II PDB 3FW3 (CRYSTAL STRUCTURE OF SOLUBLE DOMAIN OF CA4 IN COMPLEX WITH DORZOLAMIDE) LIGAND CODE = ETS (link to the list of PDB complexes) Download experimental 3D coordinates of ETS with added hydrogens | Carbonic anhydrase 2 UNIPROT P00918 CA2 more at DrugCentral | EMA | |||
