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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
LANSOPRAZOLE

LANSOPRAZOLE
DEXLANSOPRAZOLE


ATC A02BC03
ATC A02BD07
ATC A02BD03
ATC A02BD02
ATC A02BD10
ATC A02BD09
ATC A02BC53

METABOLISM
ANTIULCERATIVE
GASTRIC ACID PROTON-PUMP INHIBITORS

ORAL INTRAVENOUS

Cmax 4.6 MICROMOLAR

Tmax 1.7 HOUR

F 80 PERCENT

VD 15.7 LITER

PPB 97 PERCENT

Cl 11.1 LITER / HOUR (65 KILOGRAM)

HT 1.3 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

(H+,K+) ATPASE

POTASSIUM-TRANSPORTING ATPASE INHIBITOR CHEMBL2095173 POTASSIUM-TRANSPORTING ATPASE P20648 POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1 HOMO SAPIENS ENZYME HYDROLASEANSM (in French)

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