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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
TIZANIDINE

TIZANIDINE


ATC M03BX02

MUSCULO-SKELETAL SYSTEM
ADRENERGIC ALPHA-AGONISTS
ANTIHYPERTENSIVE

ORAL

F 40 PERCENT

VD 156 LITER (65 KILOGRAM)

PPB 30 PERCENT

Cl 42.9 LITER / HOUR

HT 2.5 HOUR

SOLUBILITY SLIGHTLY SOLUBLE IN WATER

ALPHA-2A ADRENERGIC RECEPTOR

ADRENERGIC RECEPTOR ALPHA-2 AGONIST CHEMBL2095158 ADRENERGIC RECEPTOR ALPHA-2 P08913 ALPHA-2A ADRENERGIC RECEPTOR HOMO SAPIENS MEMBRANE RECEPTOR 7TM1 SMALLMOL MONOAMINE RECEPTOR ADRENERGIC RECEPTORANSM (in French)

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