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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
METFORMIN

METFORMIN


ATC A10BA02
ATC A10BD13
ATC A10BD15
ATC A10BD11
ATC A10BD05
ATC A10BD14
ATC A10BD03
ATC A10BD10
ATC A10BD07
ATC A10BD02
ATC A10BD08
ATC A10BD17
ATC A10BD16
ATC A10BD20
ATC A10BD18
ATC A10BD23
ATC A10BD22
ATC A10BD25

METABOLISM
ANTIDIABETIC
HYPOGLYCEMIC AGENTS
MITOCHONDRIAL ACTIVITY
INHIBITOR OF CHLORIDE INTRACELLULAR CHANNEL-1 (CLIC1) (PMID25361004)

ORAL

Cmax 13.9 MICROMOLAR

Tmax 7 HOUR

F 55 PERCENT

VD 654 LITER

PPB 0 PERCENT

Cl 28.8 LITER / HOUR (65 KILOGRAM)

HT 17.6 HOUR

SOLUBILITY FREELY SOLUBLE IN WATER

Mitochondrial complex I (NADH dehydrogenase) O14561 (ACPM_HUMAN)ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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