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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| ADAPALENE
| ADAPALENE | DERMATOLOGICALS | TOPICAL | Cmax 1.1 NANOMOLAR HT 17.2 HOUR SOLUBILITY PRACTICALLY INSOLUBLE IN WATER | RETINOIC ACID RECEPTOR ALPHA RETINOIC ACID RECEPTOR BETA RETINOIC ACID RECEPTOR GAMMA | RETINOIC ACID RECEPTOR AGONIST CHEMBL2363069 RETINOIC ACID RECEPTOR P10276 RETINOIC ACID RECEPTOR ALPHA HOMO SAPIENS TRANSCRIPTION FACTOR NUCLEAR RECEPTOR NR1 NR1B NR1B1 | ANSM (in French) | |||
