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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| FLUVASTATIN
| FLUVASTATIN | CARDIOVASCULAR | ORAL | Tmax 1 HOUR F 24 PERCENT VD 22.7 LITER (65 KILOGRAM) PPB 98 PERCENT Cl 5.2 LITER / HOUR (EQN) HT 3 HOUR SOLUBILITY SOLUBLE IN WATER | 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE (HMG-COA) | 3-hydroxy-3-methylglutaryl-coenzyme A reductase UNIPROT P04035 HMGCR more at DrugCentral | EMA | |||
