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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
ATOVAQUONE

ATOVAQUONE


ATC P01AX06

ANTIPARASITIC
ANTIMALARIAL
ANTIPNEUMOCYSTIS
ANTIINFECTIVE
ANTIPROTOZOAL
ANALOG OF UBIQUINONE
MITOCHONDRIAL ELECTRON TRANSPORT

ORAL

Cmax 41.2 MICROMOLAR

F 47 PERCENT

VD 39 LITER (65 KILOGRAM)

PPB 99.9 PERCENT

Cl 0.6 LITER / HOUR

HT 62.5 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

UBIQUINOL-CYTOCHROME-C REDUCTASE COMPLEX CORE PROTEIN I, MITOCHONDRIAL (BC1)

Dihydroorotate dehydrogenase (quinone), mitochondrial Q02127 (PYRD_HUMAN)ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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