Cheminformatic Tools and Databases for Pharmacology

session 98280 - Total of 1 hits - Display   hits per page:

Add another drug(s) by one keyword:
Exemple: “nib“ and click on the Search button (do not press Enter on the keyboard)

1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
GRANISETRON

GRANISETRON


ATC A04AA02

METABOLISM
ANTIEMETIC
SEROTONIN (5HT3) ANTAGONISTS

INJECTION ORAL TRANSDERMAL SUBCUTANEOUS

Cmax 206 NANOMOLAR

VD 197 LITER (65 KILOGRAM)

PPB 65 PERCENT

Cl 51.3 LITER / HOUR (65 KILOGRAM)

HT 4.9 HOUR

SOLUBILITY READILY SOLUBLE IN WATER

5-HYDROXYTRYPTAMINE 3 RECEPTOR

PDB 2YME (CRYSTAL STRUCTURE OF A MUTANT BINDING PROTEIN (5HTBP-ACHBP) IN COMPLEX WITH GRANISETRON)

LIGAND CODE = CWB (link to the list of PDB complexes)

Download experimental 3D coordinates of CWB with added hydrogens

SEROTONIN 3A (5-HT3A) RECEPTOR ANTAGONIST CHEMBL1899 SEROTONIN 3A (5-HT3A) RECEPTOR P46098 5-HYDROXYTRYPTAMINE RECEPTOR 3A HOMO SAPIENS ION CHANNEL LGIC 5HT3ANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



Copyright © 2019 Université Côte d'Azur CNRS - All rights reserved
  | Contact |