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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
BUDESONIDE

BUDESONIDE


ATC A07EA06
ATC D07AC09
ATC R01AD05
ATC R03BA02
ATC R03AK07
ATC R03AL11
ATC R03AK15
ATC R03AK12

RESPIRATORY SYSTEM
ANTIINFLAMMATORY
BRONCHODILATOR AGENTS
CORTICOSTEROIDS
GLUCOCORTICOIDS

NASAL INHALATION ORAL RECTAL

Cmax 2.6 NANOMOLAR

Tmax 1.5 HOUR

F 9 PERCENT

VD 195 LITER (65 KILOGRAM)

PPB 87.5 PERCENT

Cl 72 LITER / HOUR

HT 2.5 HOUR

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER (LOGP=1.6)

GLUCOCORTICOID RECEPTOR

Glucocorticoid receptor UNIPROT P04150 NR3C1

more at DrugCentral

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ChEMBL
BindingDB
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