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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
CANDESARTAN CILEXETIL (has an active metabolite)

CANDESARTAN CILEXETIL


ATC C10BX19
ATC C09CA06
ATC C09DB07
ATC C09DA06
ATC C09DX06

CARDIOVASCULAR
ANTIHYPERTENSIVE
HYDROLYZED TO CANDESARTAN DURING ABSORPTION FROM THE GASTROINTESTINAL TRACT
CANDESARTAN IS A SELECTIVE AT1 SUBTYPE ANGIOTENSIN II RECEPTOR ANTAGONIST
CANDESARTAN BLOCKS THE VASOCONSTRICTOR AND ALDOSTERONE-SECRETING EFFECTS OF ANGIOTENSIN II

ORAL

SOLUBILITY PRACTICALLY INSOLUBLE IN WATER

ANGIOTENSIN II RECEPTOR AT1

Type-1 angiotensin II receptor UNIPROT P30556 AGTR1

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