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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693) | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| GUANIDINE DISCONTINUED
| GUANIDINE | CARDIOVASCULAR | ORAL | SOLUBILITY VERY SOLUBLE IN WATER | PDB 1O04 (CYS302SER MUTANT OF HUMAN MITOCHONDRIAL ALDEHYDE DEHYDROGENASE COMPLEXED WITH NAD+ AND MG2+) LIGAND CODE = GAI (link to the list of PDB complexes) Download experimental 3D coordinates of GAI with added hydrogens | Voltage-gated potassium channel UNIPROT O43525 KCNQ3 more at DrugCentral | EMA | |||
