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| 1 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DESOXYCORTICOSTERONE (is an active metabolite)
| DESOXYCORTICOSTERONE | HORMONES | - | ALDOSTERONE SYNTHASE PDB 2AA7 (MINERALOCORTICOID RECEPTOR WITH BOUND DEOXYCORTICOSTERONE) LIGAND CODE = 1CA (link to the list of PDB complexes) Download experimental 3D coordinates of 1CA with added hydrogens | Mineralocorticoid receptor UNIPROT P08235 NR3C2 more at DrugCentral | EMA | ||||
| 2 | INN | Class | Route (list) | PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that the equation t1/2 = VD / Cl * 0.693 was used | Primary Target and PDB code of Protein-Drug complex | Targets from DrugCentral | Links | |||
| DESOXYCORTICOSTERONE PIVALATE DISCONTINUED (has an active metabolite)
| DESOXYCORTICOSTERONE PIVALATE | HORMONES | INJECTION | SOLUBILITY INSOLUBLE IN WATER | ALDOSTERONE SYNTHASE PDB 4DVQ (HUMAN ALDOSTERONE SYNTHASE PMID23322723) | Mineralocorticoid receptor UNIPROT P08235 NR3C2 more at DrugCentral | EMA | |||
