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1 INNClassRoute (list)PK parameters= Cmax; Tmax; F: bioavailability; t1/2: half-life; VD: volume of distribution; Cl: clearance; PPB: plasma protein binding;(EQN means that value was calculated using VD=(Cl*t1/2)/0.693)Primary Target and PDB code of Protein-Drug complexTargets from DrugCentral Links
DEXRAZOXANE

DEXRAZOXANE


ATC V03AF02

VARIOUS
CARDIOPROTECTIVE
CHELATING AGENTS
CYCLIC DERIVATIVE OF EDTA
EXTRAVASATION OF ANTHRACYCLINE DRUGS
CATALYTIC TOPOISOMERASE II INHIBITOR (PMID25521189)

INJECTION

VD 35.4 LITER

PPB 0 PERCENT

Cl 10 LITER / HOUR

HT 2.1 HOUR

SOLUBILITY SPARINGLY SOLUBLE IN WATER

TOPOISOMERASE II

CHELATING AGENTANSM (in French)

Dailymed
Drugs.com

SIDER side effects

Chemical Probes Portal

ChEMBL
BindingDB
DrugBank



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