ZALCITABINE DISCONTINUED (has an active metabolite) | ZALCITABINE | ATC J05AF03
ANTIINFECTIVES ANTI-HIV AGENTS ANTIMETABOLITES NUCLEOSIDE AND NUCLEOTIDE REVERSE TRANSCRIPTASE INHIBITORS | ORAL | Cmax 119.4 NANOMOLAR Tmax 0.8 HOUR F 80 PERCENT VD 34.7 LITER (65 KILOGRAM) Cl 17.1 LITER / HOUR HT 2 HOUR SOLUBILITY 76.4 MILLIGRAM / MILLILITER IN WATER | DEOXYCYTIDINE KINASE PDB 2VP9 (STRUCTURAL STUDIES OF NUCLEOSIDE ANALOG AND FEEDBACK INHIBITOR BINDING TO DROSOPHILA MELANOGASTER MULTISUBSTRATE DEOXYRIBONUCLEOSIDE KINASE) LIGAND CODE = DOC (link to the list of PDB complexes) Download experimental 3D coordinates of DOC with added hydrogens | Reverse transcriptase,RNaseH UNIPROT Q72547 pol more at DrugCentral | EMA ANSM (in French) Inxight Drugs Dailymed Drugs.com SIDER side effects Chemical Probes Portal ChEMBL BindingDB DrugBank |